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Amlexanox - CAS# 68302-57-8 Size:2 mg solid Blockade is seen with TG100-115

SKU: 36736010342

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Amlexanox - CAS# 68302-57-8 Size:2 mg solid Blockade is seen with TG100-115Amlexanox, also known as AA 673 and CHX 3673, is an anti inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.

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Description

Blockade is seen with TG100-115 doses as low as 0

Smiles: O=C1CC2=C(NC3=CC=C(Br)C=C32)C2=CC=CC=C2N1

Solubility: DMSO 100 mg/mL (197

PubMed PMID: 25450629

including stimulation of Ca2+ mobilization

Amlexanox - CAS# 68302-57-8 Size:2 mg solid Blockade is seen with TG100-115Amlexanox, also known as AA 673 and CHX 3673, is an anti inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.

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