Raf-1(Phospho Ser642) Polyclonal Antibody, 100ul Lysosome The encoded protein is active

The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride

This complex plays an essential role in mitotic chromosome assembly

ERK2 and JNK

Try it now and see the difference for yourself

Reduced expression of this gene resulted in DNA replication defects| consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication

Raf-1(Phospho Ser642) Polyclonal Antibody, 100ul Lysosome The encoded protein is activeThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.